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Anthony DeSimone (May 24, 1950 – January 14, 1979), also known as Two-Gun, Tommy or Tommy D, was an Italian-American gangster and associate of the Lucchese crime family in New York. DeSimone was a grandson and nephew of Los Angeles mob bosses Rosario DeSimone and Frank DeSimone, respectively. He was married to Angelica "Cookie" Spione, but had many mistresses, including Theresa Ferrara. In the 1990 Martin Scorsese film Goodfellas, the character Tommy DeVito (played by Joe Pesci) is based on DeSimone.

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